Cinnamic acids and derivatives
Medchemexpress LLC (E)-Ethyl p-methoxycinnamate | 24393-56-4 | 99.4% | 206.24 | 1 ML
(E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic, and anti-microbial effects. It acts as an inhibitor of COX-1 and COX-2 enzymes in vitro, with IC50 values of 1.12 μM and 0.83 μM, respectively. The product is intended for research use only and is not sold to patients.
- Natural product sourced from Kaempferia galangal.
- Exhibits anti-inflammatory, anti-neoplastic, and anti-microbial effects.
- Inhibits COX-1 (IC50: 1.12 μM) and COX-2 (IC50: 0.83 μM) in vitro.
- Shows moderate inhibitory activity against α-glucosidase (IC50: 50 μM).
- Inhibits migration and tubular structure formation in HUVECs.
- Exhibits cytotoxicity in various cancer cells.
- Induces apoptosis through caspase-3/7/8/9 activation in cancer cells.
- Inhibits bFGF and heparin-induced angiogenesis.
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 10mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.6% | 339.39 | 1 ML
Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. It inhibits lipid droplet formation, increases autophagy, inhibits Apoptosis, and improves insulin resistance and insulin sensitivity.
- Potent and orally active curcumin analog
- Inhibits lipid droplet formation
- Increases autophagy
- Inhibits apoptosis
- Improves insulin resistance and insulin sensitivity
- Decreases palmitic acid (PA)-induced SREBP1 expression levels in AML12 cells
- Ameliorates insulin resistance and hepatic steatosis in mice with high-fat diet-induced obesity
Selleck Chemical LLC 2-Methoxycinnamic acid
2-Methoxycinnamic acid (AI3-11206) is a cinnamic acid with magnetic properties
Cayman Chemical FerulIc AcId ethyl ester 1g
A lipophilic derivative of ferulic acid, with increased ability to cross cell membranes; less DPPH radical scavenging capacity than ferulic acid (IC50 = 66.7 μM for FAEE vs. 44.6 μM for ferulic acid); increases the expression of HO-1, Hsp70, and Hsp72, providing neuroprotection against amyloid β-peptide
Cayman Chemical FerulIc AcId ethyl ester 10g
A lipophilic derivative of ferulic acid, with increased ability to cross cell membranes; less DPPH radical scavenging capacity than ferulic acid (IC50 = 66.7 μM for FAEE vs. 44.6 μM for ferulic acid); increases the expression of HO-1, Hsp70, and Hsp72, providing neuroprotection against amyloid β-peptide
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.6% | 339.39 | 5 MG
Curcumin 5-8 is a potent and orally active natural curcumin analog. It inhibits lipid droplet formation, increases autophagy, and inhibits apoptosis. It also improves insulin resistance and insulin sensitivity.
- Inhibits lipid droplet formation.
- Increases autophagy.
- Inhibits apoptosis.
- Improves insulin resistance.
- Improves insulin sensitivity.
Medchemexpress LLC Tyrphostin AG 528 | 133550-49-9 | MFCD01076474 | 98.0% | 306.32 | C18H14N2O3 | 10 MG
Tyrphostin AG 528 is a small-molecule protein tyrosine kinase inhibitor used as a research reagent for biochemical and cellular studies targeting EGFR and ErbB2. It is supplied as a solid with high purity and defined storage recommendations for long-term stability.
- Small-molecule inhibitor selective for EGFR and ErbB2.
- Reported IC50: EGFR 4.9 μM, ErbB2 2.1 μM.
- High purity (98.0%) suitable for preclinical research.
- Solid, light yellow to yellow appearance for easy handling.
- Molecular weight 306.32 and formula C18H14N2O3 for characterization.
- Available in small pack sizes for screening and assay development.
- Recommended storage: powder at -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC 2-Propenoic acid, 3-(2-methoxyphenyl)- | 6099-03-2 | 178.19 | 10 G
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. It is for research use only and not sold to patients.
- Purity: 99.94%
- Available in various sizes as solid or solution (10 mM in DMSO)
- Derived from plants, specifically Ranunculaceae Pulsatilla chinensis (Bunge) Regel
- Noncompetitive inhibitor of tyrosinase
- Detailed documentation available: Data Sheet, COA, SDS, Handling Instructions, HNMR, RP-HPLC
eMolecules 845823-26-9 | 2'-(3-Fluorobenzyloxy)acetophenone | Oakwood Chemical | MFCD06411645 | 244.265 | C15H13FO2 | 99.000 | CC(=O)c1ccccc1OCc1cccc(F)c1 | 1g | 537680623
2'-(3-Fluorobenzyloxy)acetophenone | Oakwood Chemical | 845823-26-9 | MFCD06411645 | 244.265 | C15H13FO2 | 99.000 | CC(=O)c1ccccc1OCc1cccc(F)c1 | 1g | 537680623